Winfried Rief Selected Research

Medically Unexplained Symptoms

1/2022	Predicting optimal treatment outcomes using the Personalized Advantage Index for patients with persistent somatic symptoms.
1/2021	Feasibility of Present-Centered Therapy for Prolonged Grief Disorder: Results of a Pilot Study.
1/2019	Cognitive Behaviour Therapy Complemented with Emotion Regulation Training for Patients with Persistent Physical Symptoms: A Randomised Clinical Trial.
11/2017	Core Outcome Domains for Clinical Trials on Somatic Symptom Disorder, Bodily Distress Disorder, and Functional Somatic Syndromes: European Network on Somatic Symptom Disorders Recommendations.
1/2017	Peripheral Immune Alterations in Major Depression: The Role of Subtypes and Pathogenetic Characteristics.
1/2014	How to use the new DSM-5 somatic symptom disorder diagnosis in research and practice: a critical evaluation and a proposal for modifications.
1/2014	The predictive value of somatic and cognitive depressive symptoms for cytokine changes in patients with major depression.
11/2009	Serotonin transporter gene promoter polymorphism and somatoform symptoms.

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Winfried Rief Research Topics

Disease

17	Pain (Aches) 01/2021 - 11/2009
8	Medically Unexplained Symptoms 01/2022 - 11/2009
8	Obesity 12/2012 - 09/2005
7	Chronic Obstructive Pulmonary Disease (COPD) 02/2019 - 01/2008
6	Chronic Pain 01/2021 - 01/2017
5	Mental Disorders (Mental Disorder) 02/2019 - 01/2014
5	Breast Neoplasms (Breast Cancer) 04/2018 - 11/2011
4	Anxiety Disorders (Anxiety Disorder) 01/2021 - 01/2017
4	Fatigue 01/2020 - 01/2006
3	Prolonged Grief Disorder 04/2022 - 01/2020
3	Death (Near-Death Experience) 09/2021 - 01/2015
3	Low Back Pain (Lumbago) 01/2020 - 01/2010
3	Somatoform Disorders (Somatoform Disorder) 02/2019 - 08/2003
3	Migraine Disorders (Migraine) 12/2017 - 09/2008
3	Back Pain (Backache) 01/2017 - 06/2010
3	Tension-Type Headache (Tension Headache) 01/2017 - 06/2008
3	Body Dysmorphic Disorders (Body Dysmorphic Disorder) 06/2010 - 06/2006
3	Headache (Headaches) 09/2008 - 01/2006
2	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2021 - 12/2011
2	Neoplasms (Cancer) 01/2021 - 01/2019
2	Depressive Disorder (Melancholia) 01/2019 - 11/2009
2	Dizziness (Lightheadedness) 01/2018 - 01/2018
2	Headache Disorders (Headache Syndromes) 01/2017 - 09/2008
2	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2017 - 01/2014
2	Sleep Initiation and Maintenance Disorders (Insomnia) 06/2015 - 09/2014
2	Psychotic Disorders (Schizoaffective Disorder) 03/2015 - 12/2011
2	Inflammation (Inflammations) 04/2012 - 10/2010
2	Tinnitus 09/2009 - 12/2008
1	Brain Injuries (Brain Injury) 08/2022
1	COVID-19 01/2022
1	Panic Disorder (Panic Attack) 11/2020
1	Borderline Personality Disorder (Personality Disorders, Borderline) 07/2020
1	Iron Deficiencies 01/2020
1	Major Depressive Disorder (Major Depressive Disorders) 01/2019
1	Wounds and Injuries (Trauma) 01/2019
1	Constipation 01/2018
1	Neurasthenia 11/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2014
1	Temporomandibular Joint Disorders (Temporomandibular Joint Disorder) 12/2013
1	Bruxism 10/2012

Drug/Important Bio-Agent (IBA)

8	Biological ProductsIBA 01/2019 - 01/2004
6	GoldIBA 02/2019 - 01/2008
5	Pharmaceutical PreparationsIBA 01/2018 - 01/2006
3	Prostaglandins DIBA 04/2022 - 01/2020
3	CytokinesIBA 02/2019 - 06/2011
3	7,7'- dimethoxy- (4,4'- bi- 1,3- benzodioxole)- 5,5'- dicarboxylic acid dimethyl ester (BDD)IBA 06/2010 - 06/2006
2	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 01/2021 - 11/2009
2	Antidepressive Agents (Antidepressants)IBA 02/2019 - 09/2014
2	Biomarkers (Surrogate Marker)IBA 11/2017 - 04/2012
2	Interleukin-6 (Interleukin 6)IBA 01/2012 - 10/2010
1	VaccinesIBA 01/2022
1	Complement System Proteins (Complement)IBA 01/2021
1	SolutionsIBA 01/2021
1	EnzymesIBA 11/2020
1	DNA (Deoxyribonucleic Acid)IBA 11/2020
1	MethyltransferasesIBA 11/2020
1	PlacebosIBA 01/2020
1	IronIBA 01/2020
1	Analgesics (Analgesic Drugs)IBA 01/2020
1	Neurotransmitter Agents (Neurotransmitter)IBA 02/2019
1	KynurenineIBA 02/2019
1	Tryptophan (L-Tryptophan)FDA Link 02/2019
1	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 01/2019
1	Amitriptyline (Elavil)FDA LinkGeneric 01/2018
1	C-Reactive ProteinIBA 01/2017
1	Interleukin-10 (Interleukin 10)IBA 01/2017
1	InterleukinsIBA 01/2017
1	Estrogen ReceptorsIBA 02/2015
1	Doxepin (Mareen)FDA LinkGeneric 09/2014
1	Histamine Antagonists (Antihistamines)IBA 09/2014
1	Narcotics (Narcotic Analgesics)IBA 09/2014
1	NeuropeptidesIBA 09/2014
1	GABA-A Receptors (GABA(A) Receptor)IBA 09/2014
1	Progesterone Receptors (Progesterone Receptor)IBA 09/2014
1	BenzodiazepinesIBA 09/2014
1	Anticonvulsants (Antiepileptic Drugs)IBA 09/2014
1	Zolpidem (Ambien)FDA LinkGeneric 09/2014
1	zopiclone (Zop)IBA 09/2014
1	Melatonin Receptors (Melatonin Receptor)IBA 09/2014
1	zaleplon (Sonata)FDA LinkGeneric 09/2014
1	Hormones (Hormone)IBA 09/2014
1	Oxygen (Dioxygen)IBA 02/2014
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2014
1	Silver Sulfadiazine (SSD)FDA LinkGeneric 01/2014
1	Leptin ReceptorsIBA 12/2012
1	Proteins (Proteins, Gene)FDA Link 12/2012

Therapy/Procedure

22	Therapeutics 08/2022 - 08/2003
10	Psychology Biofeedback (Biofeedback) 12/2017 - 08/2003
4	Pain Management 01/2020 - 07/2013
2	Palliative Care (Palliative Therapy) 09/2021 - 01/2021
2	Analgesia 01/2020 - 01/2017
2	Neurofeedback 01/2017 - 01/2014
2	Ambulatory Care (Outpatient Care) 01/2017 - 01/2014
2	Drug Therapy (Chemotherapy) 06/2015 - 11/2009
1	Relaxation Therapy (Relaxation Technique) 01/2021
1	Operative Surgical Procedures 01/2019
1	Terminal Care (Care, Terminal) 01/2015
1	Aftercare (After-Treatment) 02/2014
1	Precision Medicine 01/2014
1	Occlusal Splints 12/2013